Category Archives: Entopsis

Unmasking the Future of Cancer Detection: 10 AI Startups Leading the Charge

LinkedIN post from: Lachezar Zanev

Welcome to the future of healthcare, where Artificial Intelligence (AI) and cutting-edge technology join hands to make a significant impact on patient outcomes. As we ride the wave of this digital health revolution, one of the most promising areas of application is cancer detection and treatment. Early detection of cancer is paramount to improving survival rates, and AI holds immense potential to accelerate this process. 

Across the globe, a new breed of startups is harnessing the power of AI to pioneer innovative approaches for early cancer detection. These companies are leveraging advanced algorithms, deep

Entopsis creates PCRopsis LLC as a separate entity

Entopsis Inc. has developed a wide range of technologies in the life sciences industry, such as OpsisDx, PCRopsis, PlantOpsis, ZooOpsis, and Genurine. Each set of technologies addresses a distinct market niche, with distinct clients, key opinion leaders, business and scientific expectations, regulatory landscape, and interested investors. As such, Entopsis will create subsidiaries for each set of technologies to best address the particular business needs of each product line. The subsidiaries will hold exclusive rights to the underlying technology, while Entopsis will perform common operational tasks.

PCRopsis™ Reagent RVD mediates direct PCR for less than the competition

PCRopsis™ Reagent RVD was recently shown to mediate direct PCR amplification from viral and bacterial targets using low volumes of reagent and sample, thus drastically lowering costs and increasing testing accessibility.

Reagent RVD is a flexible direct PCR product for various research and clinical applications. The PCR testing industry is particularly price-conscious, with thin profit margins. As such, laboratories seek affordable and accurate solutions to offer clients the best services.

Recent miniaturization studies confirm Reagent RVD facilitates extraction-free RT-PCR and qPCR for less than $5 per reaction. Typically, RNA and DNA extraction kits cost $5.00 ~ $10.00 per extraction, when

The Entopsis Family Grows with the Launch of the Global Health Institute

Have you ever read about cool, new medical products / tests, only to later realize it won’t be available for years into the future (if ever)?

Entopsis is effectively a R&D company that creates novel, impactful technologies for the bio-medical space. They are best known for OpsisDx™ (single platform to diagnose diseases early through urine) and PCRopsis™ (clinical tools that make diagnostic tests more efficient). This team of hard-core scientists and engineers usually rather license technologies, than sell directly to consumers.

This is where the Global Health Institute (GHI) comes in. GHI’s mission is to de-risk new clinical technologies by

Beyond COVID-19 Testing: Reagent RVD Facilitates Extraction-free Amplification of Bacteria

Reagent RVD has proven capable of amplifying SARS-CoV-2 gene targets directly from universal viral transport (UVT) medium without the need for viral RNA extraction. However, diagnostic reference laboratories also want to use this approach for the amplification of bacterial gene targets.

The PCRopsis™ research team has extended their validation efforts in this direction. It’s been confirmed that Reagent RVD is capable of mediating extraction-free qPCR of specimens containing gram positive and negative bacteria.

To date, Reagent RVD facilitates extraction-free amplification of viral, bacterial and human gene targets directly from UVT.

This opens the door to new applications with Reagent

GIA Expands Commercialization of OpsisDx Tests

Genetics Institute of America (GIA) received IRB approval to expand its Prostate Cancer Study (GH215) utilizing OpsisDx to include: Breast, Ovarian and Lung Cancers. OpsisDx will be used to develop accurate, non-invasive tests for the early detection of these 3 additional cancers.

GIA, empowered by OpsisDx, will be able to screen people for prostate, breast, ovarian, and / or lung cancers once these 4 studies are completed. These tests are expected to detect tumors earlier than liquid biopsies and thereby outperform GRAIL (valued at over $4 billion).

The Entopsis team will continue to support GIA’s efforts of bring impactful tools

PCRopsis Reagent RVD Launched!

Is viral RNA extraction necessary for amplifying genes from coronaviruses, like SARS-CoV-2?

NOT ANY MORE!

PCRopsis Reagent RVD allows you to perform direct RT-qPCR from nasopharyngeal / oropharyngeal samples transported in BD Universal Viral Transport media or Copan ESwab.

Simple Protocol:

  1. Mix sample 1:1 with Reagent RVD
  2. Heat to 95C for 10 minutes
  3. DONE… use ~5 uL into your RT-qPCR mix (can use 5 uL into a total 20 uL reaction)

Key Features:

  • Reagent RVD is an alternative to RNA extraction
  • Offers comparable RT-qPCR results to RNA extraction procedures for many applications in 10 MINUTES
  • Cost a fraction of traditional RNA extraction procedures, with fewer steps
  • Compatible

4 OpsisDx Tests Licensed in the USA

Entopsis recently signed licensing agreements with a CLIA-certified diagnostic laboratory to commercialize 4 oncology OpsisDx tests in the USA. This represents the first step in bringing OpsisDx to market.

The Entopsis team continues to prove-out the capabilities of OpsisDx for the early detection of other cancers, infectious diseases and mental illnesses. These efforts are aimed at establishing additional partnerships globally for a variety of medical conditions so that we can offer better health outcomes to all people.

Entopsis wins Most Disruptive Technology Award

Digital photo of Venetian highway, Miami modified from photo taken by Marc Averette (CC BY-SA 3.0).

This is just hot off the press. The Greater Miami Chamber of Commerce yesterday awarded Entopsis the Most Disruptive Technology Award. The Chamber has had an illustrious history dating back to 1907 when it was chartered to take over the functions of the Miami Board of Trade and Merchants’ Association. Since inception, the Chamber has played an active role in shaping events and commercial development in Miami. Entopsis is honored to be recognized by the Chamber for being a leading innovator in Miami. Our intrepid CEO, Dr.

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